Fexomac-M
Antihistamine with Montelukast
Non Sedating Once Daily Anti-Allergic Combination
It is a combination of leukotriene receptor antagonist and an antihistamine. Safe & Well tolerated
Mechanism of Action:
The medicine is a combination of two drugs: Montelukast and Fexofenadine. The former is a leukotriene antagonist, which works by blocking the action of leukotriene (chemical messengers). This leads to reduction of swelling/inflammation in the airways passage and nose and also improves the symptoms. Whereas the Fexofenadine is an anti-allergic, works by blocking the action of Histamine, which is another chemical messenger responsible for watery eyes, runny nose and sneezing.
Indications:
Fexomac M tablets are indicated for the treatment of allergic rhinitis in adults and adolescents15 years of age and older
- Allergic Rhinitis
- Chronic Urticaria
- Blocked Or Runny Nose
- Sneezing
Common Cold Symptoms
Dosage:
Adults: One tablet once daily
Composition:
Each film coated tablet contains:
Fexofenadine hydrochloride I.P. …………………………… 120 mg Montelukast Sodium equivalent to Montelukast I.P……….. 10 mg Excipients……………………………………….. q.s.
Presentation:
Fexomac M available in 10 * 10 strip Tablet pack
USE IN SPECIFIC POPULATIONS:
Paediatric Use: Not recommended to children less than 15 years of age. The safety and efficacy of Montelukast in children less than 15 years has not been established.
Renal Impairment: There is no data of this combination in renally impaired patients.
Hepatic Impairment: No dosage adjustment is required in case of mild to moderate hepatic insufficiency.
Pregnancy: There are no studies in pregnant women. Fexomac M should be used in pregnancy only if the potential benefit outweighs the potential risk to the foetus. It may be used during pregnancy only if it is considered to be clearly essential.
Lactation: There are no studies in lactating women. Fexomac M should be used in nursing women only if the potential benefit outweighs the potential risk to the infant. It may be used in breast-feeding only if it is considered to be clearly essential
Geriatric Use: No dosage adjustment in the elderly is required.
Adverse Reactions: Common side effects include:
Fexofenadine – headache, drowsiness, dizziness and nausea. Montelukast – dyspepsia, abdominal pain, rash, dizziness, headache, fatigue, fever, trauma, cough and nasal congestion
EFFECTS ON ABILITY TO DRIVE AND USE MACHINES Fexomac M has no or negligible influence on the ability to drive and use machines. However, individuals have reported drowsiness or dizziness.
Patient Perspective: Tips
- You have been prescribed Fexomac M Tablet to help relieve symptoms of allergy such as runny nose, sneezing, watery eyes, and cough.
- Do not drink alcohol while taking Fexomac M Tablet as it may cause increased sleepiness.
- Stop taking Fexomac M Tablet at least three days before taking an allergy test as it can affect the test results.
References:
https://www.1mg.com/drugs/allegra-m-tablet-9172
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