Macrijo Pharma

Oral Antifungal

Rijotra

Tough Treatment For Tinea

Rijotra Star Quality Antifungal

Rijotra is technologically advanced Antifungal capsule’s with

Star Quality
  • Pellets are coated with Biocatalyst material blend
  •  Helps enhance the absorption of Itraconazole 
  •  Improves Bioavailability
  •  Improves Stability compared to conventional product

Studies demonstrate that one-week treatment, using these capsules, results in a clinical response rate of over 90%

Indications

Itraconazole Capsule is indicated for the treatment of following conditions;

Dermatological/Indications:

  • Dermatomycosis – Tinea Cruris & Tinea Corporis, Tinea Manuum & Tinea Pedis
  • Pityriasis Versicolor
  • Oral Candidiasis
  • Onychomycosis, caused by Dermatophytes and/or Yeasts

Composition:

Itraconazole 100/200mg Capsules.

Presentation:

Rijotra 100 mg and 200 mg Capsules are available as hard gelatin capsules containing Itraconazole pellets in 1×10’s capsule pack respectively

Gynecological Indications:

• Vulvovaginal Candidiasis

Dosage

  • Tinea Cruris & Tinea Corporis, Tinea Manuum & Tinea Pedisand Tinea Versicolor – 200 mg/day for 7 days 
  • Onychomycosis- Toenails: 200mg (2 capsules) once daily for 12. consecutive weeks
Contraindications:
  • Itraconazole capsules are contraindicated in patients with known hypersensitivity to Itraconazole or to any of the excipients.
  • Itraconazole capsules should not be administered to patients with evidence of ventricular dysfunction such as congestive heart failure (CHF) or a history of CHF except for the treatment of life-threatening
    or other serious infections.
  • Itraconazole Capsules must not be used during pregnancy (except
    for life-threatening cases).
Drugs that are contraindicated with ITRACONAZOLE capsules;
  • Analgesics Methadone
  • Anti-arrhythmics Disopyramide, Dronedarone, Quinidine
  • Anticoagulants andAntiplatelet Drugs – Ticagrelor
  • Antimigraine Drugs ergot alkaloids, such as dihydroergotamine, ergometrine (ergonovine), ergotamine, eletriptan.
  • Antineoplastics Irinotecan.
  • Antipsychotics.
  • Anxiolytics and Hypnotics
  • lurasidone, Pimozide, Triazolam
  • Antivirals Asunaprevir (boosted)
  • Calcium Channel Blockers Felodipine.
  • Cardiovascular Drugs, Ivabradine, Ranolazine
  • Diuretics Eplerenone
  • Gastrointestinal Drugs domperidone, naloxegol.
  • Lipid Regulating Drugs lomitapide, lovastatin, simvastatin
  • Urologic Drugs fesoterodine, in subjects with moderate to severe renal impairment, or moderate to severe hepatic impairment
  • Solifenacin, in subjects with severe renal impairment or moderate to severehepatic impairment.
  • Miscellaneous Drugs and Other Substances colchicine, in subjects
    with renal or hepatic impairment, eliglustat.
There is limited information regarding cross-hypersensitivity between Itraconazole and other Azole Antifungal agents. Caution should be used in prescribing ITRACONAZOLE capsules to patients with hypersensitivity to other Azoles.

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